Intoxicaties

Assessment and Management of Toxidromes in the Critical Care Unit

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Toxicology in the ICU: Part 1: general overview and approach to treatment

Poisonings, adverse drug effects, and envenomations continue to be commonly encountered. Patients often present critically ill and warrant ICU admission.…

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Toxicology in the ICU: Part 2: specific toxins

This is the second of a three-part series that reviews the generalized care of poisoned patients in the ICU. This…

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Toxicology in the ICU: part 3: natural toxins

This is the third article of a three-part series that reviews the care of poisoned patients in the ICU. This…

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Antidote use in the critically ill poisoned patient

The proper use of antidotes in the intensive care setting when combined with appropriate general supportive care may reduce the…

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Should we consider the infusion of lipid emulsion in the resuscitation of poisoned patients?

The use of intravenous lipid emulsions (ILEs) as antidote in local anaesthetic systemic toxicity has gained widespread support following convincing…

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Dialysis in the poisoned patient

Patients who ingest toxic substances may require extracorporeal removal of the poisons or their toxic metabolites if native renal clearance…

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Acetylcysteine for acetaminophen poisoning

A 25-year-old man presents to the emergency department with a toothache. During the evaluation, the physician determines that the patient…

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The serotonin syndrome

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Neuroleptic Malignant Syndrome: Focus on Treatment and Rechallenge

Objective: To review evidence for the treatment of neuroleptic malignant syndrome (NMS) and to discuss how to rechallenge patients with…

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