Hematologie
Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and organ…
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The most important adverse effect of antithrom-botic treatment is the occurrence of bleeding. In the case ofsevere bleeding in a…
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The direct-acting oral anticoagulants (DOACs) have been increasingly used over vitamin K antagonists in recent years because they do not…
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This article describes the pharmacology of approved parenteral anticoagulants. These include the indirect anticoagulants, unfractionated heparin (UFH), low-molecular-weight heparins (LMWHs),…
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Venous thromboembolism (VTE), including pulmonary embolism (PE) and deep venous thrombosis (DVT), is a common and severe complication of critical…
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BackgroundAnemia and cardiovascular disease Approximately seven million people in the United Kingdom, and 30% of patients admitted to the ICU…
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Three decades ago, transfusion-related acute lung injury (TRALI) was considered a rare complication of transfusion medicine. Nowadays, the US Food…
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This document aims to summarize the current literatureguiding the use of red cell transfusion in critically ill patientsand provides recommendations…
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BackgroundSevere trauma continues to represent a global public health issue and mortality and morbidity in trauma patients remains substantial. A…
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