Farmacokinetiek en farmacodynamiek
Tsai D, et al. Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill. Curr Opin Crit Care 2015
Robert JA, et al. Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions. Lancet Infect Dis 2014
Wong G, et al. How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients? BMC Infectious diseases 2014
Continu of intermitterend
Roberts JA, et al. Continuous versus intermittent ß-lactam infusion in severe sepsis. Am J Respir Crit Care Med 2016
Abdul-Aziz MH, et al. Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis. Intensive Care Med 2016.