Gepost in: Hematologie

The Coagulopathy of Chronic Liver Disease

Conventional wisdom is that chronic liver disease is an acquired bleeding disorder. However, the imbalance between procoagulant and anticoagulant activities can also lead to thrombosis. Studies are needed to assess the value of anticoagulants.




Armando Tripodi, Ph.D., and Pier Mannuccio Mannucci, M.D.


N Engl J Med 2011; 365:147-156 DOI: 10.1056/NEJMra1011170