Gepost in: Hematologie

Heparin-Induced Thrombocytopenia

HIT is characterized by a platelet-count fall of more than 50% at 5 to 10 days after the start of heparin and hypercoagulability. Platelet factor 4–heparin antibody testing has a high negative, but low positive, predictive value. Treatment involves therapeutic-dose anticoagulation.

NVIC-Academy-uitgelicht-50

 

Auteur(s):

Andreas Greinacher, M.D.

 

Publicatie:
N Engl J Med 2015; 373:252-261 DOI: 10.1056/NEJMcp1411910