Intensivist

Pancreatitis Werkgroep Nederland

Acute Liver Failure

Acute liver failure is a rare but life-threatening critical illness that occurs most often in patients who do not have…

Acuut leverfalen

Nutrition in the Acute Phase of Critical Illness

Critically ill patients requiring vital organ support in the intensive care unit (ICU) commonly have anorexia and may be unable…

Does the use of indirect calorimetry change outcome in the ICU? Yes it does

Purpose of reviewTo review the recent findings on metabolic monitoring and possible beneficial effects of an adequate nutrition therapy, based…

Early enteral nutrition in critically ill patients: ESICM clinical practice guidelines

Purpose: To provide evidence-based guidelines for early enteral nutrition (EEN) during critical illness. Methods: We aimed to compare EEN vs.…

Pharmacokinetic/pharmacodynamic considerations for the optimization of antimicrobial delivery in the critically ill

Purpose of reviewAntimicrobials are very commonly used drugs in the intensive care setting. Extensive research has been conducted in recent…

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

Infections in critically ill patients are associated with persistently poor clinical outcomes. These patients have severely altered and variable antibiotic…

How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?

High mortality and morbidity rates associated with severe infections in the critically ill continue to be a significant issue for…

Continuous versus Intermittent b-Lactam Infusion in Severe Sepsis

Rationale: Optimization of b-lactam antibiotic dosing for critically ill patients is an intervention that may improve outcomes in severe sepsis.…